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Happy New Years eve...

Started by Mugwump, December 31, 2017, 05:18:12 AM

Previous topic - Next topic

Mugwump

....as 2017 comes to a close, any plans for the 2018 year?

Where's NADA this year?.....they may bring back the GCCA Classic in Chicago?....where's the ACA?    Anyone traveling near a forum member here?
Jon

?Life should not be a journey to the grave with the intention of arriving safely in a pretty and well preserved body, but rather to skid in broadside in a cloud of smoke, thoroughly used up, totally worn out, and loudly proclaiming ?Wow! What a Ride!? ~ Hunter S. Thompson

wsantia1

Willie

Too Many Fish. Not Enough Tanks.

Mugwump

Jon

?Life should not be a journey to the grave with the intention of arriving safely in a pretty and well preserved body, but rather to skid in broadside in a cloud of smoke, thoroughly used up, totally worn out, and loudly proclaiming ?Wow! What a Ride!? ~ Hunter S. Thompson

BallAquatics

Stephan asked me if I'd be interested in going to Interzoo with him.....

Dennis

Mugwump

Quote from: BallAquatics on December 31, 2017, 08:10:12 AM
Stephan asked me if I'd be interested in going to Interzoo with him.....

Dennis

....cool.....ya gonna go?

https://www.tradefairdates.com/Interzoo-M4882/Nuremberg.html

https://www.interzoo.com/en/review

Interzoo in Nuremberg is the world's largest trade fair for pet supplies and offers a purely professional environment. Whether you feed and care products, pet accessories, or new products and trends for specialty subjects such as animals in the garden, horse stables and boutique. Interzoo is the ideal platform for international exhibitors to present their offer here the most important decision makers in the industry. Exhibitors here benefit from direct contact with their target audiences.

On the whole the organisers welcomed on the 4 days of the fair, from 26. May to 29. May 2016, about 1800 exhibitors from 61 countries and 39000 visitors from 117 countries on the Interzoo in Nuremberg.

The Interzoo will take place on 4 days from Tuesday, 08. May to Friday, 11. May 2018 in Nuremberg.
Jon

?Life should not be a journey to the grave with the intention of arriving safely in a pretty and well preserved body, but rather to skid in broadside in a cloud of smoke, thoroughly used up, totally worn out, and loudly proclaiming ?Wow! What a Ride!? ~ Hunter S. Thompson

Ron Sower

..Nothing as exciting as Interzoo, I'm sure....

...The first thing is to get thru the Spring Fling...it's taking a lot of time and energy, and Lucy seems to have gravitated to being the HMFWIC [that's head main female what's in charge!] of the committee of the 6 chairmen...that's a good spot for her, but she is putting a lot of pressure on herself which often transfers to me...but that's okay...it invokes that "for better or worse" thing in the vows... :D :D :D :D

...We may bop over to Maui at the end of March...2 sets of friends coming in different weeks of April...after all that is over, I want us to do mare 1-3 day trips here in AZ...this state is freaking beautiful and full of wild west history that I want to learn more about...

...I'm sure Lucy will want us to take a trip back WA in the summer to visit the daughter and gdaughter...

Happy Aquariuming,
Ron

LizStreithorst

Quote from: Mugwump on December 31, 2017, 05:18:12 AM
....as 2017 comes to a close, any plans for the 2018 year?

Where's NADA this year?.....they may bring back the GCCA Classic in Chicago?....where's the ACA?    Anyone traveling near a forum member here?

NADA's in New Jersey this year and I don't think I'll go.  There are people I'll miss seeing but just a few.

Is there not a big Angelfish convention and show anywhere?  At ACA they look down their noses at tank bred fish.  They call Discus hybrids not even knowing what a hybrid is.  I want a 3 day fish party among kindred spirits.
Always move forward. Never look back.

LizStreithorst

Quote from: Ron Sower on December 31, 2017, 10:44:46 AM
..Nothing as exciting as Interzoo, I'm sure....

...The first thing is to get thru the Spring Fling...it's taking a lot of time and energy, and Lucy seems to have gravitated to being the HMFWIC [that's head main female what's in charge!] of the committee of the 6 chairmen...that's a good spot for her, but she is putting a lot of pressure on herself which often transfers to me...but that's okay...it invokes that "for better or worse" thing in the vows... :D :D :D :D

...We may bop over to Maui at the end of March...2 sets of friends coming in different weeks of April...after all that is over, I want us to do mare 1-3 day trips here in AZ...this state is freaking beautiful and full of wild west history that I want to learn more about...

...I'm sure Lucy will want us to take a trip back WA in the summer to visit the daughter and gdaughter...

Ron, I don't know from personal experience but I have heard that taking separate vacations can make the heart grow fonder.  I've also heard the opposite.  If I were you, which I'm not, I would encourage miss lucy go on her visit and tell her that you'll take off in the RV and explore the beauty of your State.
Always move forward. Never look back.

Mugwump

Quote from: LizStreithorst on December 31, 2017, 11:40:36 AM
Quote from: Mugwump on December 31, 2017, 05:18:12 AM
....as 2017 comes to a close, any plans for the 2018 year?

Where's NADA this year?.....they may bring back the GCCA Classic in Chicago?....where's the ACA?    Anyone traveling near a forum member here?

NADA's in New Jersey this year and I don't think I'll go.  There are people I'll miss seeing but just a few.

Is there not a big Angelfish convention and show anywhere?  At ACA they look down their noses at tank bred fish.  They call Discus hybrids not even knowing what a hybrid is.  I want a 3 day fish party among kindred spirits.

WHAT?.......the ACA has a wide display of tank bred fish...angels too...

Jon

?Life should not be a journey to the grave with the intention of arriving safely in a pretty and well preserved body, but rather to skid in broadside in a cloud of smoke, thoroughly used up, totally worn out, and loudly proclaiming ?Wow! What a Ride!? ~ Hunter S. Thompson

Mugwump

got this Liz...?

.............
Discus genetics..

Alleles are different varieties of a single gene. For example, we often talk about a mutant allele and a wildtype allele for some gene. Discus like most all animals are diploid meaning they have 2 alleles for each gene. One allele came from the mother and the other allele came from the father. When it comes time to reproduce, discus make sperm and eggs through meiosis that each only have 1 allele (haploid) chosen at random from the 2 they carry. Fertilization brings two alleles back together to make a diploid fish.

An essential step in understanding Discus genetics is connecting the observed segregation of traits in a cross to specific alleles of different genes. This can be confusing so I've assembled the following guide to help you know what to look for. To use this guide, you should first identify phenotypes that are segregating in a cross. Segregating means that some progeny have the trait and some don't. You should then try to match the pattern of segregation to the following examples while keeping in mind the possible sources of confusion.

A gene is a chunk of DNA on a chromosome which typically encodes a protein. Alleles are different varieties of a particular gene. The wildtype allele by definition encodes a protein with normal function. A mutant allele may encode a protein with no function, it might encode a protein with a new function, or it might encode a protein with normal function but turned on in different cells than normal.

Recessive alleles. Recessive alleles are only seen phenotypically when homozygous. They are denoted with lowercase italics. For example, if a is a recessive allele and + is the wildtype allele then the possible combinations of alleles in an individual are
genotype: phenotype
+/+: wildtype
a/+: wildtype
a/a: mutant

The possible crosses are as follows with results shown genotype (phenotype)
a/+ x +/+: 50% a/+ (wildtype), 50% +/+ (wildtype)
a/+ x a/+ = 25% a/a (mutant), 50% a/+ (wildtype), 25% +/+ (wildtype)
a/a x a/+ = 50% a/a (mutant), 50% a/+ (wildtype)
a/a a/a = 100% a/a (mutant)

If a trait disappears in one generation and reappears in the next generation, then it is most likely recessive (the other option is that epistasis as explained below is hiding a dominant phenotype).

Dominant alleles. Dominant alleles have the same phenotype when heterozygous or homozygous. They are denoted with uppercase italics. For example, if B is a dominant allele and + is the wildtype allele then the possible combinations of alleles in an individual are:
genotype: phenotype
+/+: wiltype
B/+: mutant
B/B: mutant

The possible crosses are as follows with results shown genotype (phenotype)
B/+ x +/+: 50% B/+ (mutant), 50% +/+ (wildtype)
B/+ x B/+ = 25% B/B (mutant), 50% B/+ (mutant), 25% +/+ (wildtype)
B/B x B/+ = 50% B/B (mutant), 50% B/+ (mutant)
B/B B/B = 100% B/B (mutant)

Dominant alleles cannot hide except through epistasis.

Semidominant alleles. Semidominant alleles have one phenotype when heterozygous and a different (often more pronounced) phenotype when homozygous. They are denoted with uppercase italics. For example, if C is a semidominant allele and + is the wildtype allele then the possible combinations of alleles in an individual are:
genotype: phenotype
+/+: wiltype
C/+: mutant phenotype 1
C/C: mutant phenotype 2

The possible crosses are as follows with results shown genotype (phenotype)
C/+ x +/+: 50% C/+ (phenotype 1), 50% +/+ (wildtype)
C/+ x C/+ = 25% C/C (phenotype 2), 50% C/+ (phenotype 1), 25% +/+ (wildtype)
C/C x C/+ = 50% C/C (phenotype 2), 50% C/+ (phenotype 1)
C/C x C/C = 100% C/C (phenotype 2)

Possible sources of confusion.
Some traits will not follow the above rules. Common reasons are as follows:
Small sample size. When you flip a fair coin there is a 50% chance it will be heads and 50% chance it will be tails. But this does not guarantee that your results will always be 50:50. If you flip a coin twice, there is a 50% chance you'll get one head and one tail and a 50% chance you'll get the same thing twice. The more you flip it, the more likely that the results will be near 50%. The same math holds for alleles and is called a binomial distribution. There are binomial calculators online that will tell you the chances of getting observed vs. predicted that might help you decide if your numbers match the predictions closely enough to fit the above predictions are not (http://stattrek.com/online-calculator/binomial.aspx). For the a/+ x a/+ cross, if you look at 40 progeny, the chances of seeing N a/a individuals is:
N p
5 2.7%
6 5.3%
7 8.6%
8 11.8%
9 14%
10 14%
11 13%
12 11%
13 7.6%
14 5%
15 2.8%

Incomplete penetrance. Incomplete penetrance means that not all of the animals that should have a phenotype based on their genotype, do have a phenotype. Incomplete penetrance causes there to be more phenotypically wildtype progeny than reflected in the numbers above. Whether or not an incompletely penetrant allele shows a phenotype can be based on what other genes (modifiers) are present in the genome, on the environment, or on chance. If your trait consistently follows one of the above patterns but just with lower number of mutants, then it might be due to an incompletely penetrant allele.
Epistasis. Epistasis means that the phenotype of one genetic locus (gene) hides the effect of another genetic locus (gene). For example albino mutants cannot make the black pigment melanin and are recessive. In Pigeon blood mutants which is dominant, the melanin producing cells called melanocytes are scattered rather than localized in stress bars. Imagine the following cross:
Pb/+; alb/+ x +/+; alb/+ (one parent is phenotypically Pigeon blood and neither are albino). The progeny are:
12.5%: Pb/+; +/+ (Pigeon blood)
12.5%: +/+; +/+ (wildtype)
25%: Pb/+; alb/+ (Pigeon blood)
25%: +/+; alb/+ (wildtype)
12.5%: Pb/+; alb/alb (albino)
12.5%: +/+; alb/alb (albino)
If you sum up the phenotypes you get 37.5% Pigeon blood, 25% albino, and 37.5% wildtype. If you were just focused on Pigeon blood then these numbers would be confusing. To understand the numbers you must understand that albino is epistatic to Pigeon blood (the double mutant has the same phenotype as albino). In this case a recessive allele of one gene is hiding the phenotype of a dominant allele of another gene.
Multiple genes with the same phenotype. It is possible for two different genetic loci (genes) to have the same phenotype when mutated. For example, it seems that there are two different albino mutations in Discus. They are both all white when homozygous but one of them has red retinas (rabbit eyes, true albino) and the other has maroon retinas (grape eye, lutino). If alleles for both genes were present in a cross, then the ratio of the offspring would appear weird if you didn't consider this possibility. To determine if two alleles are for the same gene or for different genes you can do a complementation test. For recessive alleles, you determine if having 1 copy of 1 allele and 1 copy of the other allele gives the same phenotype as having 2 copies of either allele. If it does then it is the same gene, if not (it complements) then they are different genes.
Lethality. It is possible that an allele might give one phenotype when heterozygous and result in lethality in homozygotes. This appears to be the case for snakeskin.
Polygenic. Some traits are controlled by more than one genetic locus in such a way that it is difficult to establish any kind of pattern between genotype and phenotype by only looking at one gene.
Sex linked. In mammals and birds sex is determined by sex chromosomes. In mammals, XX is female and XY is male. In birds, WW is male and WZ is female. The Y and Z chromosomes typically lose genes over the course of evolution until they only have the sex determination gene on them. This means that male mammals have only one copy of X-linked genes so dominant and recessive no longer apply. For example, color blindness is recessive in females but males with one bad copy are color blind. However, many fish species do not use sex chromosomes for determining sex, and sex determination systems evolve quite quickly. As far as I know, it is unknown how sex is determined in Discus.

Note: You should not think that dominant genes are "stronger" and recessive genes are "weaker". Dominant and recessive implies nothing except whether the heterozygotes have one phenotype or the other. Likewise you should not say that an allele is more dominant or more recessive. This is like saying an animal is more dead than another. Dominant and recessive can't be modified by a superlative.
Jon

?Life should not be a journey to the grave with the intention of arriving safely in a pretty and well preserved body, but rather to skid in broadside in a cloud of smoke, thoroughly used up, totally worn out, and loudly proclaiming ?Wow! What a Ride!? ~ Hunter S. Thompson

Ron Sower

Quote from: LizStreithorst on December 31, 2017, 11:52:20 AM
Quote from: Ron Sower on December 31, 2017, 10:44:46 AM
..Nothing as exciting as Interzoo, I'm sure....

...The first thing is to get thru the Spring Fling...it's taking a lot of time and energy, and Lucy seems to have gravitated to being the HMFWIC [that's head main female what's in charge!] of the committee of the 6 chairmen...that's a good spot for her, but she is putting a lot of pressure on herself which often transfers to me...but that's okay...it invokes that "for better or worse" thing in the vows... :D :D :D :D

...We may bop over to Maui at the end of March...2 sets of friends coming in different weeks of April...after all that is over, I want us to do mare 1-3 day trips here in AZ...this state is freaking beautiful and full of wild west history that I want to learn more about...

...I'm sure Lucy will want us to take a trip back WA in the summer to visit the daughter and gdaughter...

Ron, I don't know from personal experience but I have heard that taking separate vacations can make the heart grow fonder.  I've also heard the opposite.  If I were you, which I'm not, I would encourage miss lucy go on her visit and tell her that you'll take off in the RV and explore the beauty of your State.
...Liz, she's been up there a couple times without me, which is just fine...but I'll probably go for a short visit with her this summer because the weather will be fine i enjoy short family visits and visiting the friends back in the ole 'hood....and we both like doing the short trips together...
Happy Aquariuming,
Ron